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Generic Name: Levofloxacin (Ophthalmic) 0.50%
Manufacturer/Distributor: Drug International Ltd.
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✅ Description:
Indications
An antibiotic called Levoflox is used to treat bacterial eye infections. Preventing the spread of harmful germs reduces the infection's symptoms. Levoflox should only be used externally. As directed by your doctor, take it for the prescribed amount of time.
Pharmacology
Levofloxacin eye drops are a type of topical ophthalmic arrangement that may be sterile. It might be a synthetic, broad-spectrum, third-generation fluoroquinolone bactericidal anti-microbial that is effective against both Gram-positive and Gram-negative ocular pathogens. It works by inhibiting the enzymes DNA gyrase and bacterial topoisomerase IV, which are necessary for DNA replication, translation, repair, and recombination.
Dosage and administration
0.5% eye drop:
- Grown-ups and children 1 year of age and older:
- Days 1 and 2: Instill 1-2 drops within the influenced eye(s) every 2 hours whereas wakeful, up to 8 times per day.
- Days 3 through 7: Instill 1-2 drops within the influenced eye(s) each 4 hours whereas alert, up to 4 times per day.
1.5% eye drop:
- Grown-ups and children 6 a long time of age and older:
- Days 1 through 3: Instill one to two drops within the influenced eye(s) each 30 minutes to 2 hours whereas alert and around 4 and 6 hours after retiring.
- Day 4 through treatment completion: Instill one to two drops within the influenced eye(s) each 1 to 4 hours whereas awake.
- Children <1 year: Security and adequacy of Levofloxacin underneath 1 year of age have not been established.
Interaction
Particular medication interaction considers have not been conducted with levofloxacin eye drops. But the systemic organization of a few quinolones has appeared to promote plasma concentrations of theophylline, meddled with the digestion system of caffeine, and improve the impacts of the verbal anticoagulant warfarin and its subordinates.
Contraindications
Patients having a history of sensitivity to Levofloxacin, other quinolones, or any of the medication's ingredients should not take it.
Side effects
Side impacts happened as were roughly 1-3% of patients which will incorporate transitory obscured vision, fever, outside body sensation, migraine, transitory visual burning, visual torment or inconvenience, pharyngitis, and photophobia. Less than 1% of patients included unfavorably susceptible responses, cover edema, visual dryness, and visual tingling.
Pregnancy and lactation
Pregnancy Category C. Levofloxacin ought to be utilized amid pregnancy as it were on the off chance that the potential advantage legitimizes the potential hazard to the baby. Levofloxacin has not been measured in the human drain. Caution ought to be worked out when Levofloxacin eye drops are managed by a nursing mother.
Precautions and Warnings
Drawn-out utilization may result in the excess of non-susceptible living beings, counting organisms. In case superinfection happens, suspend utilization and established elective treatment.
Storage Conditions
Eye drops ought to be secured from light, stored in a cool (15°-25° C), and dry put & keep out of reach of children.
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